Postdoctoral Research Assistant in Structural Biology Crystallography, Institute of Structural and Molecular Biology Department of Biological Sciences, Birkbeck, Malet Street, London

Full time, fixed term appointment for up to 3 years (ref 10583)

We are seeking a motivated Postdoctoral Research Assistant to undertake structural analysis of the mechanism of action and inhibition of the kinesin-8 mitotic motor in the research team lead by Dr Carolyn Moores.

The project involves using cryo-electron microscopy to elucidate the nucleotide-dependent interaction of microtubule binding by this molecular motor protein. It will involve structure determination by cryo-electron microscopy and image processing of the motor-microtubule complex in the presence and absence of a specific inhibitor, as well as biochemical manipulation of the motor-microtubule interaction.

The project is funded by CRUK and involves collaboration with several international groups. The appointee will be a member of a team working on various aspects of cytoskeleton dynamics and will also interact with members of the Birkbeck Electron Microscopy group http://people.cryst.bbk.ac.uk/~ubcg16z/empage.html<http://people.cryst.bbk.ac.uk/%7Eubcg16z/empage.html>.

Applicants should have a PhD in Structural Biology, Biophysics, Biochemistry or a related area, and have relevant research publications.

Salary: Grade 7. Starting salary of £33,804 (inclusive of London Allowance of £2,934 per annum), followed by annual increments to £38,722 per annum.

The closing date for completed applications is Friday 2 September 2011.

Interviews are due to be held Wednesday 21 September 2011.

Please click here<http://jobs.bbk.ac.uk/fe/tpl_birkbeckcollege01.asp?s=FoQnTYvIgXJoLlXgd&jobid=41426,4525361248&key=26618394&c=545634347765&pagestamp=segspknrqwtgpjzlgu> for further information and to apply.

Informal enquiries should be made to Dr Carolyn Moores, Biological Sciences, Birkbeck, Malet Street, London WC1E 7HX (e-mail: c.moores@mail.cryst.bbk.ac.uk<mailto:c.moores@mail.cryst.bbk.ac.uk>); School web page: http://www.bbk.ac.uk/biology/ in the first instance.

Birkbeck is an equal opportunities employer and encourages applications from all candidates irrespective of gender, ethnicity, age, disability, religious belief and sexual orientation.

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