{"id":312,"date":"2010-12-10T00:27:59","date_gmt":"2010-12-10T00:27:59","guid":{"rendered":"https:\/\/blogs.unc.edu.ar\/jin\/?p=312"},"modified":"2012-02-24T03:42:25","modified_gmt":"2012-02-24T03:42:25","slug":"phd-and-postdoc-position","status":"publish","type":"post","link":"https:\/\/blogs.unc.edu.ar\/jin\/2010\/12\/10\/phd-and-postdoc-position\/","title":{"rendered":"PhD AND POSTDOC POSITION"},"content":{"rendered":"<p><span class=\"Apple-style-span\" style=\"font-family: Arial;font-size: 11px\">The laboratory of Immunology (Department of Clinical Chemistry, Microbiology and&nbsp;<\/span><span class=\"Apple-style-span\" style=\"font-family: Arial;font-size: 11px\">Immunology, Ghent University, BELGIUM) has a world-renowned reputation in the field of&nbsp;lymphocyte development and is looking for talented and highly motivated researchers to join&nbsp;our team. The lab has recently established high-level expertise in the generation and culture&nbsp;of human embryonic stem cells and induced pluripotent stem cells, that were also able to&nbsp;differentiate into hematopoietic precursor cells(HPC), NK cells and T cells.&nbsp;In this novel research project, we wish to use zinc finger nucleases in human pluripotent&nbsp;stem cells to enable site-specific editing of the genome, thereby providing unprecedented&nbsp;research opportunities for functional gene studies in human. We wish to establish this&nbsp;technology to generate human pluripotent stem cells with specific gene deletions or reporter&nbsp;genes to study gene function in the differentiation of HPC, T and NK cells from pluripotent&nbsp;stem cells.&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;font: 11px Arial\">The lab has the following positions available : &nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\"><strong>Postdoc Position&nbsp;<\/strong><\/p>\n<p style=\"margin: 0px;font: 11px Arial\">The post-doc will be responsible for implementing the zinc-finger nuclease technology in&nbsp;human pluripotent stem cells to generate constitutive and conditional gene deletions by&nbsp;homologous recombination. In addition, he\/she will target reporter genes in the constitutively&nbsp;expressed AAVS1 locus. This will enable him\/her to further develop and manage his\/her own&nbsp;project. The post-doc will also be responsible for transferring this technology onto PhD&nbsp;students and technicians within the lab. &nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">The applicant should be a real team-player, have a relevant PhD in (bio)medical or biological&nbsp;sciences and hands-on experience with molecular techniques such as design of DNA&nbsp;constructs for targeted genome editing, recombination technology and\/or other DNA cloning&nbsp;technology. Experience with embryonic stem cells, cell culture and\/or flow cytometry is an&nbsp;asset.&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">The position is open starting January 1st 2011 and is available for 4 years.&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\"><strong>PhD Positions&nbsp;<\/strong><\/p>\n<p style=\"margin: 0px;font: 11px Arial\">Within the same research project, PhD positions are available to study the function of&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">specific genes (for example Bcl11b and CCR9) in the differentiation of human HPCs, T and&nbsp;NK cells from pluripotent stem cells that will harbor either a deletion for the gene of interest,&nbsp;or a reporter gene that will allow tracing of cells that express that gene.&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">Applicants should have a relevant masters degree in (bio)medical or biological sciences and&nbsp;should be willing to apply for personal research grants at the FWO and\/or IWT.&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">The positions are open starting January 1rst 2011 and are available for 4 years.&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">For further information, please contact&nbsp; <strong>bart.vandekerckhove@ugent.be<\/strong>,&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\"><strong>georges.leclercq@ugent.be<\/strong> or <strong>tom.taghon@ugent.be<\/strong> .&nbsp;<\/p>\n<p style=\"margin: 0px;font: 11px Arial\">Applications should be send by email to <strong>jean.plum@ugent.be&nbsp;<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The laboratory of Immunology (Department of Clinical Chemistry, Microbiology and&nbsp;Immunology, Ghent University, BELGIUM) has a world-renowned reputation in the field of&nbsp;lymphocyte development and is looking for talented and highly motivated researchers to join&nbsp;our team. The lab has recently established high-level expertise in the generation and culture&nbsp;of human embryonic stem cells and induced pluripotent stem cells, [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[73,19],"tags":[],"class_list":["post-312","post","type-post","status-publish","format-standard","hentry","category-especializaciones-maestrias-doctorados","category-doctorados-y-postdocs"],"_links":{"self":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts\/312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/comments?post=312"}],"version-history":[{"count":5,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts\/312\/revisions"}],"predecessor-version":[{"id":1910,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts\/312\/revisions\/1910"}],"wp:attachment":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/media?parent=312"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/categories?post=312"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/tags?post=312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}