{"id":2285,"date":"2012-05-03T01:08:10","date_gmt":"2012-05-03T01:08:10","guid":{"rendered":"https:\/\/blogs.unc.edu.ar\/jin\/?p=2285"},"modified":"2012-05-03T01:08:49","modified_gmt":"2012-05-03T01:08:49","slug":"post-doctoral-position","status":"publish","type":"post","link":"https:\/\/blogs.unc.edu.ar\/jin\/2012\/05\/03\/post-doctoral-position\/","title":{"rendered":"Post-doctoral Position"},"content":{"rendered":"

Post-doctoral Position to work on<\/span><\/b><\/p>\n

 <\/span>The epigenetic variation in the distribution of the transcription machinery in rat<\/span><\/b><\/p>\n

A two years post-doctoral position<\/b> is open at the Integrative Biology and Molecular Genetics Department (SBIGeM) on the Saclay campus of the CEA. The position is available immediately and will be closed when a suitable candidate is found.<\/span><\/p>\n

The position is funded within the framework of the Euratrans project<\/b> (European large-scale functional genomics in the rat for translational research; www.euratrans.eu<\/a>). The project uses state-of-the-art and emerging large-scale technologies and advanced computation in an expanded multi-disciplinary approach to identify gene networks and genomic mechanisms underlying common diseases.  <\/span>The work will be performed in the laboratory “Transcriptional Regulation of Genomes” headed by Dr Michel Werner.<\/span> <\/span>Within this project, the post-doctoral fellow will investigate the genome-wide distribution of RNA polymerase II and transcription factors in tissues of rat inbred lines to discover epigenetic variations that might relate to predisposition to diseases.<\/span><\/p>\n

The successful candidate will have a strong background in molecular biology and functional genomics. Prior knowledge in the analysis of high throughput sequencing data will be an advantage.<\/span><\/p>\n

The laboratory is located southwest of Paris<\/b> (France<\/b>). Information can be found on the web sites of the team <\/span>http:\/\/www-dsv.cea.fr\/ibitecs\/sbigem\/lrege\/transcription<\/span><\/a><\/span>.<\/span><\/p>\n

Interested candidates should contact: Dr. Michel Werner<\/b>    <\/span>+33-(0)1 6908 9342 \/ michel.werner@cea.fr<\/a><\/span><\/span><\/p>\n

Selected references of the team:<\/span><\/b><\/p>\n

Carrière et al. (2012) Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells. Nucl. Acids Res. 40, 270-283.<\/span><\/span><\/p>\n

Soutourina, J. et al. (2011) Direct RNA polymérase II – Mediator interaction required for transcription in vivo<\/i>. Science<\/i>, 331, 1451-1454.<\/span><\/span><\/p>\n

Esnault, C. et al. (2008) Mediator-dependent recruitment of TFIIH modules in preinitiation complex. Mol. Cell 31<\/i>, 337-346.<\/span><\/span><\/p>\n

Ghavi-Helm, Y. et al. (2008) Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription. Genes Dev.<\/i> 22, 1934-1947.<\/span><\/span><\/p>\n

Guglielmi, B. et al. (2007) TFIIS elongation factor and Mediator act in conjunction during transcription initiation in vivo<\/i>. Proc. Natl. Acad. Sci. USA<\/i> 104, 16062-16067.<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Post-doctoral Position to work on  The epigenetic variation in the distribution of the transcription machinery in rat A two years post-doctoral position is open at the Integrative Biology and Molecular Genetics Department (SBIGeM) on the Saclay campus of the CEA. The position is available immediately and will be closed when a suitable candidate is found. […]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[],"class_list":["post-2285","post","type-post","status-publish","format-standard","hentry","category-doctorados-y-postdocs"],"_links":{"self":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts\/2285","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/comments?post=2285"}],"version-history":[{"count":2,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts\/2285\/revisions"}],"predecessor-version":[{"id":2287,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/posts\/2285\/revisions\/2287"}],"wp:attachment":[{"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/media?parent=2285"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/categories?post=2285"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.unc.edu.ar\/jin\/wp-json\/wp\/v2\/tags?post=2285"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}